April 2, 2012, Masterpiece was released from Madonna's twelfth studio album MDNA.

"Masterpiece" by Madonna was written for the soundtrack of the 2011 film W.E. The song was later included on her twelfth studio album MDNA (2012). It served official radio release in the United Kingdom on April 2, 2012, to promote the album. Madonna composed the song alongside Julie Frost and Jimmy Harry, and produced it with William Orbit. "Masterpiece" is a midtempo pop ballad which is reminiscent of her works from the 1990s. The song garnered positive reviews from contemporary critics, who praised its lyrical content and Madonna's vocal performance.

"Masterpiece" won the Best Original Song category at the 69th Golden Globe Awards, but was deemed ineligible for the similar category at the 84th Academy Awards. Its Golden Globe nomination sparked a red carpet rivalry between Madonna and singer Elton John. "Masterpiece" peaked at number one in Russia, while reaching the lower regions of the charts in the Czech Republic, Japan, South Korea and the United Kingdom. It was performed by Madonna on The MDNA Tour (2012), where she was accompanied by Basque musicians Kalakan trio. The performance was considered a highlight of the tour.